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Christopher N Mayhew Selected Research

3,4-dihydroxybenzohydroxamic acid

1/2005Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease.
6/2004In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease.
11/2002Suppression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea.

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Christopher N Mayhew Research Topics

Disease

5Neoplasms (Cancer)
06/2014 - 07/2004
4Carcinogenesis
04/2022 - 09/2007
3Infections
12/2014 - 11/2002
3Murine Acquired Immunodeficiency Syndrome (MAIDS)
01/2005 - 11/2002
2Gaucher Disease (Gaucher's Disease)
10/2019 - 01/2015
2Fatty Liver
01/2019 - 06/2018
2Fanconi Anemia (Fanconi's Anemia)
01/2016 - 10/2014
2Hepatocellular Carcinoma (Hepatoma)
06/2014 - 05/2010
2Splenomegaly
06/2004 - 11/2002
2Hypergammaglobulinemia (Hyperimmunoglobulinemia)
06/2004 - 11/2002
1Cholestasis
04/2022
1Liver Failure
04/2022
1Cystic Fibrosis (Mucoviscidosis)
12/2021
1Neuroinflammatory Diseases
10/2019
1Fibrosis (Cirrhosis)
01/2019
1Inflammation (Inflammations)
01/2019
1Inborn Genetic Diseases (Disease, Hereditary)
06/2018
1Hepatomegaly
06/2014
1Congenital Malabsorptive Diarrhea 4
02/2011
1Diabetes Mellitus
02/2010
1Retinoblastoma (Glioblastoma, Retinal)
04/2008
1Virus Diseases (Viral Diseases)
06/2004
1Aneuploidy (Aneuploid)
05/2004
1Nijmegen Breakage Syndrome
04/2004
1Disease Progression
11/2002
1Retroviridae Infections (Infection, Retrovirus)
11/2002

Drug/Important Bio-Agent (IBA)

6DNA (Deoxyribonucleic Acid)IBA
01/2016 - 11/2002
4AcidsIBA
10/2019 - 11/2002
3Proteins (Proteins, Gene)FDA Link
10/2014 - 04/2004
33,4,5-trihydroxybenzamidoximeIBA
01/2005 - 11/2002
33,4-dihydroxybenzohydroxamic acidIBA
01/2005 - 11/2002
3Pharmaceutical PreparationsIBA
01/2005 - 11/2002
2GlucosidasesIBA
10/2019 - 01/2015
2CarcinogensIBA
10/2011 - 09/2007
2Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
01/2005 - 11/2002
2Hydroxyurea (Hydrea)FDA LinkGeneric
01/2005 - 11/2002
1Zonula Occludens-2 ProteinIBA
04/2022
1Mutant Proteins (Protein, Mutant)IBA
12/2021
1Glial Fibrillary Acidic ProteinIBA
10/2019
1Messenger RNA (mRNA)IBA
10/2019
1Sterol Esterase (Hormone-Sensitive Lipase)IBA
01/2019
1Nonesterified Fatty Acids (NEFA)IBA
01/2019
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019
1Virulence Factors (Pathogenicity Factors)IBA
12/2014
1Benzene (Benzole)IBA
06/2014
1XenobioticsIBA
06/2014
1Peroxisome ProliferatorsIBA
06/2014
1Diethylnitrosamine (N-Nitrosodiethylamine)IBA
10/2011
1Transcription Factors (Transcription Factor)IBA
02/2011
1palbociclibIBA
05/2010
1Insulin (Novolin)FDA Link
02/2010
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
04/2008
1Transforming Growth Factor beta3 (TGF beta 3)IBA
04/2008
1Transforming Growth Factor beta (TGF-beta)IBA
04/2008
1Didanosine (Videx)FDA LinkGeneric
01/2005
1Antiviral Agents (Antivirals)IBA
01/2005
1Polo-Like Kinase 1IBA
07/2004
1abacavir (Ziagen)FDA Link
06/2004
1GuanineIBA
06/2004
1AntimetabolitesIBA
05/2004
1Free RadicalsIBA
11/2002

Therapy/Procedure

4Therapeutics
12/2021 - 11/2002
2Transplantation
10/2019 - 02/2010
1Intravenous Infusions
10/2019
1Radio Frequency Identification Device
06/2018